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Carcinoid Syndrome Market Is Expected To Grow During The Forecast Period (2019-2032), DelveInsight

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Carcinoid Syndrome Market Is Expected To Grow During The Forecast Period (2019-2032), DelveInsight

April 27
04:42 2022
Carcinoid Syndrome Market Is Expected To Grow During The Forecast Period (2019-2032), DelveInsight

DelveInsight added a report on “Carcinoid Syndrome Market“. It covers an overview, its causes, signs and symptoms, and therapies. Major players are involved in developing therapies for Carcinoid Syndrome. The launch of emerging therapies will significantly impact the Carcinoid Syndrome market.

 

Carcinoid Syndrome Overview

Carcinoid Syndrome (CS) refers to a combination of symptoms, physical manifestations, and abnormal laboratory findings. Carcinoid syndrome is seen in individuals who have an underlying carcinoid tumor that has spread to the liver. Carcinoid tumors are well-differentiated neuroendocrine tumors with secretory properties, releasing serotonin, along with a number of other active peptides. These tumors can arise anywhere along the primitive gut and are therefore found in the bronchial tree (airways) and along the gastrointestinal tract. The tumor cells can also migrate (metastasize) to the liver.

 

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Some of the key features of the Carcinoid Syndrome Market Report

  • Carcinoid tumors are rare, with only 27 new cases per million diagnosed in the U.S. per year.
  • The Carcinoid tumors syndrome affects males and females equally.
  • Carcinoid syndrome may be more prevalent than suspected because diagnosis is difficult and sometimes overlooked; some patients may not exhibit all three of the hallmark symptoms of flushing, wheezing, and diarrhea.
  • Carcinoid Tumor companies such as Aquestive Therapeutics, Crinetics Pharmaceuticals, and several others.
  • Carcinoid Tumor therapies such as AQST-305-SF, Paltusotine, and several others.

 

Carcinoid Syndrome Symptoms

  • Red Skin flushing
  • Facial skin lesions
  • Diarrhea
  • Difficulty breathing
  • Rapid heartbeat
  • Wheezing

 

Carcinoid Syndrome Diagnosis

Diagnosis is best achieved with a multimodality approach including biochemical investigation, radiological and nuclear imaging, and finally histological (tissue biopsy) confirmation where possible. Standard treatment is surgery to remove the entire tumor where possible and reduce (debulk) any metastases. Hepatic artery catheterization with injection of embolic inert particles alone or mixed with chemotherapy has been very effective in many patients with liver metastases.

 

Carcinoid Syndrome Cause

The underlying cause of carcinoid tumors remains unclear. Some studies have suggested risk factors such as smoking and dietary intake. However, further research is needed to confirm these findings. In the majority of cases tumors are slow-growing and can produce hormonal chemical substances such as serotonin, bradykinins, tachykinins and prostaglandins. If the original carcinoid cells spread (metastasize) to the liver, these substances are no longer broken down to their inactive form and are released into the systemic (main) circulation, causing the signs and symptoms of carcinoid syndrome. When tumors affect organs other than the gastrointestinal tract, such as the ovaries, carcinoid syndrome can occur in the absence of liver metastases.

 

Carcinoid Syndrome Treatment

Carcinoid Syndrome Treatment is based on controlling specific signs and symptoms due to hormones released by the tumor itself, as well as treating the neoplasm. Standard treatment is surgery to remove the entire tumor where possible and reduce (debulk) any metastases. In gastrointestinal tumors this will involve resection of the affected area. For bronchial (airway) lesions, procedures such as lobectomy, sleeve resection or pneumonectomy may be required depending on the location of the mass. Debulking of liver metastases can be done by surgical excision or by newer techniques such as cryoablation and radiofrequency ablation. Hepatic artery catheterization with injection of embolic inert particles alone or mixed with chemotherapy has been very effective in many patients with liver metastases. Octreotide (Sandostatin) injections are the mainstay for symptomatic management of carcinoid syndrome.

 

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Carcinoid Syndrome Market Insights

Systemic therapy should be used to control humorally mediated symptoms when the cancer spreads elsewhere. Patients benefit from specific drugs that either suppress production of vasoactive amines or block the peripheral effects. These agents include alpha-adrenergic blocking drugs, cyproheptadine, and H2-receptor blockers. Little evidence suggests that chemotherapy, either traditional or by continuous infusion, helps improve patient survival rates. However, failure to respond to one chemotherapy combination does not necessarily mean another combination will also be ineffectual.

 

Carcinoid Syndrome Emerging Therapy

The dynamics of the Carcinoid Syndrome market is anticipated to change in the coming years owing to the improvement in healthcare spending across the world. Key players, such as Aquestive Therapeutics, Crinetics Pharmaceuticals and others are involved in developing drugs for Carcinoid Syndrome. The launch of potential emerging therapies such as AQST-305-SF (Aquestive Therapeutics), and Paltusotine (Crinetics Pharmaceuticals) are expected to change the treatment landscape during the forecast period (2021–2030).

 

Carcinoid Syndrome Epidemiology Segmentation

  • Total Incidence cases
  • Total Diagnosed patient pool
  • Total Treated patient pool

 

Carcinoid Syndrome Market Drivers

  • Advent of new concepts in pathophysiology and therapeutic interventions
  • Growing R&D
  • Advances in the molecular pathogenesis of NENs

 

Carcinoid Syndrome Market Barriers

  • Negative impact on quality of life
  • No sequence of different treatments

 

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Table of content

  1. Key Insights
  2. Executive Summary of Carcinoid Syndrome
  3. Competitive Intelligence Analysis for Carcinoid Syndrome
  4. Carcinoid Syndrome: Market Overview at a Glance
  5. Carcinoid Syndrome: Disease Background and Overview
  6. Patient Journey
  7. Carcinoid Syndrome Epidemiology and Patient Population
  8. Treatment Algorithm, Current Treatment, and Medical Practices
  9. Carcinoid Syndrome Unmet Needs
  10. Key Endpoints of Carcinoid Syndrome Treatment
  11. Carcinoid Syndrome Marketed Products
  12. Carcinoid Syndrome Emerging Therapies
  13. Carcinoid Syndrome: Seven Major Market Analysis
  14. Attribute analysis
  15. 7MM: Market Outlook
  16. Access and Reimbursement Overview of Carcinoid Syndrome
  17. KOL Views
  18. Market Drivers
  19. Market Barriers
  20. Appendix
  21. DelveInsight Capabilities
  22. Disclaimer
  23. About DelveInsight

 

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About Us

DelveInsight is a Business Consulting and Market research company, providing expert business solutions for life science vertical and offering quintessential advisory services in the areas of R&D, Strategy Formulation, Operations, Competitive Intelligence, Competitive Landscaping, and Mergers & Acquisitions.

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